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The FDA has published two important Citizen Petitions about opioid use on regulations.gov:

The 1st Suggests genetic damage due to opioid use may be causing a dysfunction in the nervous system
The 2nd Suggests that opioid addiction may not be the proper diagnosis

There are four important steps to help us end this opioid crisis. We are assuming you reviewed the two Citizen Petitions and want to take the next steps. 

Smith Genetics Research